While we are looking at the cells through the microscope, they only appear in the 2D shape but they do come in all 3D sizes and shapes. Clearly, a 2D image is sufficient for the basic study but if you wish to go deeper, you won’t get sufficient amount of thins to study from. With the help and collaboration of international researchers, it has been looked upon now on the ways that can overcome this problem by creation a 3D view of the cells. Such a technology will allow the scientists to gather much more information about cells.
With this tech, It has been clearly observed that a single cell is nearly 10 micrometers and inside it, there’s a nuclear core which is 5 micrometers. Below nuclear, there are tiny holes, called as ‘nuclear pore complex’ that are the gate that regulates the messenger bio-molecules, but distances between one-50th and one-20th of a micrometer. The new technology, entitled as MEANS (mirror-enhanced, axial-narrowing, super-resolution) microscopy, goes by obtaining thicknesses of the cell at various focal points, providing the researchers the capability to see the differences in layers of the cell. The method works by building cells on custom-made, small mirrors. The method works by building cells on custom-made, small mirrors. A glass coverslip is placed on top of the cells, then further, adding the mirror in place of a usual slide in a wide-field or confocal microscope.