Genes Find Their Partners Without Match-Makers

Identical segments of DNA bind together automatically without any help of other molecules, a new research finds.

Genes are segments of DNA which carry the encoded genetic information of our body. Every gene encodes a specific character or function in living beings. But, genes require regular repair due to damages.

During one of these processes of repair, named homologous recombination, a damaged gene is replaced with the same gene of an extra copy of DNA. Genetic disorders arise due to errors caused to due to replacement of genes by wrong ones. One such example is Progeria which causes rapid aging.

Recombination proteins help in copying and replacement of genes during homologous recombination process, which also aids in reproduction and evolution as it involves genes of each parent to get combined and shuffled.

A research at the Imperial College London and National Institutes of Health experimentally reveals that DNA molecules having same genetic codes pair up together without any outside help and guidance in spite of existence of 20,000 genes in human DNA and the complex network of DNA strands bundled up together into chromosomes.

The experiments proved that if two small identical DNA strands are randomly mixed up in a solution then they would independently group together with the sections of DNA similar to them.

The joint result of Harvard and Imperial study presents the proof for joining together of long identical DNA segments within the same molecule. Truly, DNA will never stop surprising us!


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